NICOTINAMIDE 99% FOR BIOCHEMISTRY
Nicotinamide is used as a medicine for treating skin conditions such as acne and rosacea. You are taking anticonvulsants such as carbamazepine: Nicotinamide may increase the blood levels and risk of side effects of this drug.
Nicotinamide is a building block (active component) of coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phopshate (NADP). It may be used as a substrate of nicotinamide phosphoribosyltransferase (NAMPT, EC 2.4.2.12), the rate-limiting enzyme for NAD(+) biosynthesis and an important signaling molecule. It is an amide derivative of vitamin B3 and a PARP inhibitor.
Dosage
Most niagen supplement brands recommend taking 250–300 mg per day, the equivalent of 1–2 capsules per day depending on the brand. Most niagen manufacturers recommend taking 250–300 mg of nicotinamide riboside per day.